LeRoy International - The Company

3RFlex Frequently Asked Questions Part 1

Q1: What is collagen?

Q2: What is collagen hydrolysate?

Q3: What is the difference between collagen, collagen hydrolysate and gelatine?

Q4: What raw material does 3Rflex use?

Q5: How is collagen hydrolysate absorbed and how does it reach the artilage?

Q6: Why take a collagen hydrolysate supplement?

Q7: Why is collagen hydrolysate specially important for cartilage in comparison to other proteins?

Q8: Can I take it when I'm on other medication?

Q9: Are there any side effects of taking collagen hydrolysate?

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Q1: What is collagen?

A1: Collagen is the most abundant protein in the human and animal body representing 30% of total body protein. Collagen gives the structure to tendons, cartilage tissue bones and connective tissue.

The collagen molecule is formed by 3 intertwined protein chains building a triple helix structure (with a molecular weight of -300kD). The triple helix structure of collagen is responsible for the strength and flexibility of cartilage tissue.

The amino acid composition of collagen includes 30% glycine and 25% proline and hydroxyproline. The amino acids make collagen different from other proteins and are of great importance for collagen synthesis.

Q2: What is collagen hydrolysate?

A2: Collagen hydrolysate is collagen (from skin, bone and cartilage) broken down by a natural process (hydrolysis) to facilitate easy absorption into the blood stream.

Since collagen hydrolysate has the same amino acid composition as collagen it is an ideal component for cartilage regeneration. Collagen hydrolysate stimulates collagen synthesis, as proven by a laboratory study by Oesser et al. (Cell & Tissue Research 311:393-9; March 2003).

Clinical studies with patients suffering from osteoarthritis revealed the positive effect of collagen hydrolysate on joint health (e.g. pain reduction, reduced medication, improved physical function).

The beneficial effect of collagen hydrolysate on osteoarthritis is patented (European patent No 0254289 Agents for the treatment of osteoarthritis, 1986, based on a study by Prof Adam). Collagen hydrolysate received GRAS status (Generally Recognized As Safe) by the US Food and Drug Administration (FDA).

Due to its special production process collagen hydrolysate does not gel and is soluble in cold water.

Q3: What is the difference between collagen, collagen hydrolysate and gelatine?

A3: Collagen is the most abundant protein in the human and animal body representing 30% of total body protein. Collagen gives the structure to tendons, cartilage tissue bones and connective tissue.

Gelatine is produced from collagen. It has gelling properties and is used in the food industry (e.g. emulsifier, gel-former, taste and color enhancer), in the pharmaceutical industry (e.g. for capsules, as blood replacement, agent for vitamin coating) and in the photo industry (e.g. basis of film and photographic paper).

Collagen hydrolysate is also produced from collagen but by a different process. The amino acid composition of collagen and collagen hydrolysate are very similar. This similarity gives collagen hydrolysate an important role in building new cartilage. Research has shown that collagen hydrolysate stimulates collagen synthesis: this effect was proven by a laboratory study by Oesser et al. (Cell & Tissue Research 311:393-9; March 2003).

Q4: What raw material does 3Rflex use?

A4: Bovine (skin of cow), hide spilt and bone chips are the raw materials of collagen hydrolysate. Collagen hydrolysate is manufactured by using only selected raw materials from healthy animals that have been approved by veterinary authorities for human consumption.

Q5: How is collagen hydrolysate absorbed and how does it reach the cartilage?

A5: Oesser et al. (Journal of Nutrition 129:1891-95; 1999) conducted experiments with isolated segments of the intestine show that collagen fragments can pass through the intestinal wall (10-15% of these proteins; in a high molecular form of up to 50kD) and reach the blood stream. Accumulation of radio-labeled collagen hydrolysate can subsequently be seen in cartilage.

Q6: Why take a collagen hydrolysate supplement?

A6: The stress placed on our joints means that they are prone to damage in the longer term. Cartilage is worn out and sometime lost. Unfortunately the body is sometimes unable to produce sufficient new cartilage to counteract this loss.

By taking a collagen hydrolysate supplement we can provide our body with the essential building blocks needed for the formation of joint cartilage. Collagen hydrolysate is used as nutritional supplement for the prevention and treatment of degenerative diseases like osteoarthritis.

Q7: Why is collagen hydrolysate specially important for cartilage in comparison to other proteins?

A7: The amino acid composition of collagen hydrolysate corresponds exactly to that of collagen - the predominant protein in cartilage.

Q8: Can I take it when I'm on other medication?

A8: Yes, since collagen hydrolysate is a food and not a pharmaceutical drug, there are no contraindications or side effects.

Q9: Are there any side effects of taking collagen hydrolysate?

A9: Collagen hydrolysate is a food and not a pharmaceutical drug. It has a strong safety profile: Extensive studies demonstrate no significant side effects: in very rare cases diarrhea or flatulence were observed.

Collagen hydrolysate is neither a mutafgen nor a toxic substance not a teratogen.

Disease Information: Disease  |  Deadly Disease  |  Lupus  |  Diabetes  |  Celiac  |  Yellow Fever  |  Flu  |  Osteoporosis  |  Tuberculosis  |  Multiple Sclerosis  |  Shingles  |  Crohn's  |  Lyme  |  Eating  | 

3RFlex Frequently Asked Questions Part 2

Q10 What is the best time to take 3R Flex?

Q11 Can gastric patient take 3RFlex?

Q12 Can we take other supplement and medicines together with 3RFlex?

Q13 Why after gout patient take 3RFlex, they get more pain at their joint?

Q14 Can pregnant women take 3RFlex?

Q15 Why after take 3RFlex we get more pain at their joint?

Q16 How long does the pain last?

Q17 Can 3RFlex help Cancer patient?

Q18 Why after take 3RFlex get itchy and redness on the face?

Q19 Why after take 3RFlex get headache or acne?

Q20 Can high blood pressure patient take 3RFlex?

Q21 Can diabetic take 3RFlex?

Q22 How long will i need to take 3RFlex?

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A10: The best time to take 3RFlex is immediately after wake up in the morning but before breakfast.

Q11: Can gastric patient take 3RFlex?

A11: YES, you can. It is recommended for those who have stomach upset or gastric to take 3RFlex after breakfast. If the consume 3RFlex on empty stomach, they may experience some problem due to their digestion. As such they may become bloated, gas, even has gastric. So it is better they consume after food.

Q12: Can we take other supplement and medicines together with 3RFlex?

A12: YES, you can. You may take other medicines or supplements together with 3RFlex. It is a food and not a drug, there are no contradictions or side effects.

Q13: Why after gout patient take 3RFlex, they get more pain at their joint?

A13: Reaction due to the damage tissue and repair process in the problem area.

Q14: Can pregnant women take 3RFlex?

A14: YES, they can as 3RFlex is a food and does not has any effect on mother or the baby. We recommend that pregnant women to practice caution when taking any food supplement even though they are safe as during pregnancy their body is more sensitive to changes in diet. If in doubt, please consult your doctor for advice.

Q15: Why after take 3RFlex we get more pain at their joint?

A15: This maybe due to the extensiveness of the damage joints and the amount of the toxicity in their body.

Q16: How long does the pain last?

A16: This is very dependent on the amount of damages of the joint, level of health and healing process. The pain may last from a few days to one month.

Q17: Can 3RFlex help Cancer patient?

A17: YES, it can help them because 3RFlex can repair and rebuild their body cell especially who gone through chemotherapy treatment. The treatment can damage your body cell.

Q18: Why after take 3RFlex get itchy and redness on the face?

A18: This could be due to toxicity in the blood. Recommendation: Try taking 3R BioChlorella to cleanse the blood and may then continue taking 3RFlex.

Q19: Why after take 3RFlex get headache or acne?

A19: It could be due to the heatiness. Try reduce the intake to half (1/2) a sachet.

Q20: Can high blood pressure patient take 3RFlex?

A20: YES, they can. 3RFlex is a food. The hydrolyzed collagen in 3RFlex can help to strengthen our health.

Q21: Can diabetic take 3RFlex?

A21: YES, they can. Fructose content in 3RFlex has a low glycemic index which does not affect the insulin level in DIABETICS. It is recommended that DIABETICS patient to START with half (1/2) a sachet for a MONTH and one (1) sachet after that. DIABETICS patient are reminded to reduce their CARBOHYDRATE intake.

Q22: How long will i need to take 3RFlex?

A22: Expert recommended a daily intake of one sachet 3RFlex for at least three (3) months. Research shows that if you stop taking it, the symptoms may reoccur. Therefore, once you have benefited from 3RFlex, a maintenance dose of one (1) sachet take every other day is recommended.

Disease Information: Disease  |  Deadly Disease  |  Lupus  |  Diabetes  |  Celiac  |  Yellow Fever  |  Flu  |  Osteoporosis  |  Tuberculosis  |  Multiple Sclerosis  |  Shingles  |  Crohn's  |  Lyme  |  Eating  | 

The BENEFITS of Collagen

Do you know what is collagen?

1. What is collagen?

Collagen is the most abundantly available and most widely distributed protein compound in our body.

• 70% of our skin textures are made up of collagen
• 80% of our sinews and tendons are made of collagen
• about 100% of cartilages are made of collagen
• 80% of bones are also made of collagen; COLLAGEN forms matrix to HOLD CALCIUM, PHOSPHORUS, and other minerals together to FORM our BONES
• Smooth muscles like blood vessels, digestive tract and organs are made of collagen

• Main component of hair, skins, and nails
• TO RETAIN CALCIUM IN OUR BODY - MISCONCEPTION ABOUT CALCIUM ALONE COULD STRENGTHEN OUR BONES.

2. COLLAGEN and GOOD HEALTH

Collagen is widely distributed protein, it has a direct significance to the normal functioning of our body organ systems.

Research has shown that if there is any dysfunction or abnormal changes in our collagen, it will cause the following:

1. Osteoarthritis
2. Osteoporosis
3. Systematic Lupus Eryhromatosus (SLE)
4. other Connective Tissue Diseases (CTDs)

Under normal circumstances, as we age (peak at 25-30 years old), our body's collagen would diminish (0.5% to 1.0% yearly).

This will cause our skin to loose elasticity and subsequently become thinner as we age.

Our fatty tissues shrink progressively while our sweats and sebaceous (oil) glands reduce their secretions. Pigmentation's and wrinkles will start to appear alongside other signs of aging which would result in an aged complexion.

Appropriate replacement of collagen will help prevent aging and promote beauty and good health. At the same time, it helps prevent osteoporosis, arthritis, and promotes recovery from other illnesses.

3. Types of Collagen?

There are 19 types of collagen, each with their own individual functions.

Collagen Helps in Improving Health and Promoting Recovery

1. Beautify our Complexion

1.1 Hydration

Collagen is rich with "Natural Hydrating Factor", a

hydrophilic material, which combines with the protein

on our skin to replace our skin's diminishing collagen

and maintain hydration.

This prevents drying and cracking of our skin.

1.2 Prevents Wrinkle

Collagen can fully absorbed through our skins and

it forms part of our skin, making it

looks firm, turgid, and more elastic.

1.3 Restoration

• Collagen has a special restorative property. It can combine with it's surrounding structure and thus helps to restore any damages.

1.4 Skin Elasticity

• Collagen can make our skin soft, turgid and supple. It smoothes the stratum corneum (outher skin), stimulates blood circulation and improves metabolism resulting in reduce wrinkles and smooth radiant complexion.

2. Prevent Osteoporosis

2.1 Our body's bone density peaks at about 30 years' old. Sebsequently, it diminishes by 0.5-1.0% each year.

2.2 Our bones are composed of:

• Bone Mineral; i.e. Calcium; Collagen and non-collageneous substances.
• Collagen makes up more than 90% of our bone bulk. It's vital in maintaining our bone structure.

Liken to building a house, collagen acts as the concrete while calcium acts as steel bars; both are equally important.

2.3 When our body lacks of collagen, we cannot keep Calcium molecules in their places. This affects our bone density and resulting in OSTEOPOROSIS.

2.4 What is Osteoporosis?

• Common disease of BONE.
• Decreasing density of BONE.
• Fragile and Easily FRACTURES.
• Cause of DISABILITY and IMMOBILITY (for 50-65 years old people)

3. Protect Joints and Prevent Joint Erosion (Arthritis - Joint Inflammation)

3.1 A normal joint consist of cartilage, synovial membrane, synovial fluid and ligaments.

3.2 Cartilage, located at both ends of a bone could protect it from erosion during movement.

At such 90% of cartilage is made of Aggrecan and Collagen II.

3.3 When the structures mentioned above are functioning well, the cartilages can well withstand the weight applied to it.

When the collagen content is reduced, the bonds of Aggrecan and Collagen will be weakened, causing the cartilage to become unstable under pressure; thus it is easily susceptible to erosion.

Symptoms after cartilage damages:

· Pain

· Inflexible

· Swollen

3.4 Type of Arthritis:

• Rheumatoid Arthritis
• Gout

  

4. Beautiful Hair and Shinny Nails

HAIR

4.1 Microscopic examination of a cross section of our hair shows:

• The core, which is called the medulla, and in the middle of it is made of collagen
• While the outer layer is hair cuticle(scales)

4.2 Collagen can directly affect the thickness, elasticity and moisture content of our hair, whereas the cuticles give the hair its shine and texture. But the most important function of the cuticles is to protect the inner collagen structure.

4.3 The use of hairdryer, hair perm and dyeing can damage the collagen structure in our hair causing hair splits, fragmentation and hair loss.

4.4 Since our hair derives its nutrients from its roots below the scalps, we can help it to regain its previous shine and beauty if we provide collagen supplement to its roots at the appropriate time.

NAILS

4.5 A normal nail is pink, firm, curved downwards and shinny smooth. All these qualities are associated with collagen.

4.6 Frequent collagen supplement can help our nails to grow strong, and healthy. As a result, we have shinny nails.

5. Promote Firm and Shapely Breasts

5.1 Breasts are made up of suspensory ligaments and fatty tissue, while its size id determined by the breast margin and the amount if fat content. The shape and firmness of breast it largely dependent on the support of its suspensory ligaments.

5.2 Collagen is the main component of suspensory ligament.

5.3 In order to have healthy and shapely breasts, one should have adequate intakes of fat and also should have a collagen supplement of to encourage the development of suspensory ligaments to maintain its shape and firmness.

6. Weight Loss and Improve Health Weight Loss

6.1 Collagen hydrolysate could increase the metabolism of muscle and fat tissue. When our body's insulin level is high, catabolism (buring of fat) will be markedly reduced. When insulin is low, the catabolism fatty acid is increased.

Research has shown that, out body's insulin level is the lowest when we are fasting or deep sleep; Collagen supplements can sufficiently prolong the duration of low insulin level in our body. Thus, the fatty acid has more time to undergo catabolism, causing significant weight loss.

6.2 According to research, collagen hydrolysate works best for weight lost when taken just before sleep after abstinence from food for three to four hours.

Improve Health

6.3 People who lack growth hormone usually have underdeveloped muscles. Growth hormone is continuously released during the childhood and teenage years. Growth hormone is secreted most deep sleep and least during light sleep.

6.4 Research shows that collagen can improve the level of deep sleep and thus improve muscle development resulting in a healthy muscular build.

7. Enhance the Human Immune System

Collagen can also:

7.1 Enhance our immune system

7.2 Increase cellular multiplication

7.3 Strengthen the corneal stroma to ensure normal arrangement to maintain translucency.

7.4 Strengthen the function of internal organs, protect liver and rejuvenate the hepatocytes (Liver Cells).

7.5 Protects hepatocytes, increase the secretion of insulin, increase breast secretion, reduce constipation, prevent the spread of cancer cells and prevent aging.

REMARKS:

1. Collagen has a long history of being used as food and medicine.

These products are usually accepted by food regulators as safe products. Pharmaceutical-grade Collagen Hydrolysate (PCH) comes from pharmaceutical grade connective tissue hydrolysate.

2. Clinical studies have shown that: Daily intake of 10g of PCH can reduce the pain in knee and pelvic osteoarthritis patients.

THE EFFECTS OF SPINE PROBLEMS

3R Flex Can Helps on.Please follow this link to.THE EFFECTS OF SPINE PROBLEMS

What is 3RFlex?

What is 3RFlex?

in Brief.....

"3RFlex is a proprietary food formulation of nutrients for the bone and joints nutrition consists of Hydrolysed Collagen (HC). Hydrolysed collagen, a protein derive from the hydrolysis of collagen provides the raw material for the formation of collagen in our body. This ingredient played important role in supplying the needed nutrients and building block for the production of collagen in joints and bone."

Overview

Joints and Bone Problems Musculoskeletal diseases are one of leading causes of severe disability and long term pain suffered by more than 400 million of people around the world. Commons musculoskeletal diseases are Osteoarthritis, Osteoporosis and Gout. In the United States, Osteoarthritis is the leading cause of disability and chronic pain suffered by 50% of those aged 60 years above. One of the major causes of Musculoskeletal diseases is degeneration of the cartilage due to normal daily wear and tear of our joints.

The World Health Organization (WHO) has designated the year 2000 - 2010 as the 'Decade of Bone and Joints' to highlight and create the awareness on the seriousness of Bone and Joints diseases to the world government.

LeRoy International offers the ultimate solution to Bone and Joints Health - 3RFlex.

3R Flex

3RFlex is a proprietary food formulation of nutrients for the bone and joints nutrition consists of Hydrolyzed Collagen (HC), Vitamins such as Vitamin C, A, B , D3 and Minerals such as Calcium, Magnesium and Zinc.

It provides the necessary nutrients and active ingredients for the promotion of bone and joints health. Hydrolyzed collagen, a protein derive from the hydrolysis of collagen provides the raw material for the formation of collagen in our body.

The active ingredient Hydrolyzed Collagen is produced in Germany with proprietary process that breakdown the collagen of cow hides into smaller molecules of around 3,000 Dalton. This ingredient played important role in supplying the needed nutrients and building block for the production of collagen in joints and bone.

Benefits of 3RFlex

• Supply Bone and Joints nutrients.

• Helps to stimulate the production collagen.

• Helps to maintain the healthy cartilage tissue.

• Helps in the overall improvement of joints health.

References:

1. Adam et al., 1991 - Supplementation of HC reduce pain and improve functional ability of joints.

2. Oesser et al., 2003 (Cell & Tissue Research , 311, 393-399) - showed in tissue culture HC stimulate collagen synthesis and secretion of chondrocytes with degraded collagen.

3. Dr. James Rippe - The Joint Health Prescription recommends 10g of HC with vitamin B and C, calcium and magnesium.